Mandelamine

Pronunciation: meth-EN-a-meen
Generic Name: Methenamine
Brand Name: Examples include Hiprex and Urex

Mandelamine is used for:

Preventing urinary tract infections.

Mandelamine is a urinary antiseptic. It works by concentrating in the urine as formaldehyde, which kills bacteria in the urine.

Do NOT use Mandelamine if:

• you are allergic to any ingredient in Mandelamine


• you have kidney problems


• you are taking a sulfonamide (eg, sulfamethizole)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Mandelamine:

Some medical conditions may interact with Mandelamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have diarrhea, a stomach infection, liver or kidney problems, or gout, or you are severely dehydrated

Some MEDICINES MAY INTERACT with Mandelamine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sulfonamides (eg, sulfamethizole) because they may decrease Mandelamine's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Mandelamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Mandelamine:

Use Mandelamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Mandelamine by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Before you begin using an antacid, check with your doctor or pharmacist.


• If you miss a dose of Mandelamine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Mandelamine.

Important safety information:

• It is important that your urine be acidic while you are taking Mandelamine. Check with your doctor to see if you should eat or avoid certain foods to keep your urine acidic.


• Mandelamine may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Mandelamine.


• Lab tests, including urine pH, may be performed while you use Mandelamine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• PREGNANCY and BREAST-FEEDING: It is not known if Mandelamine can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Mandelamine while you are pregnant. Mandelamine is found in breast milk. If you are or will be breast-feeding while you use Mandelamine, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Mandelamine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Mandelamine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Mandelamine:

Store Mandelamine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Mandelamine out of the reach of children and away from pets.

General information:

• If you have any questions about Mandelamine, please talk with your doctor, pharmacist, or other health care provider.


• Mandelamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Mandelamine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Mandelamine resources

• Mandelamine Side Effects (in more detail)
• Mandelamine Use in Pregnancy & Breastfeeding
• Drug Images
• Mandelamine Drug Interactions
• Mandelamine Support Group
• 1 Review for Mandelamine - Add your own review/rating

• Mandelamine Advanced Consumer (Micromedex) - Includes Dosage Information


• Mandelamine Concise Consumer Information (Cerner Multum)


• Methenamine Monograph (AHFS DI)


• Methenamine Prescribing Information (FDA)


• Hiprex Prescribing Information (FDA)

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